OECD 431: In Vitro Skin Corrosion Test

OECD 431: In Vitro Skin Corrosion Test

OECD 431 is a standardized in vitro test method designed to assess the corrosion potential of substances on human skin. This test evaluates the effects of chemicals on skin tissue to determine whether they cause irreversible damage, which is crucial for regulatory compliance and product safety assessment. The assay involves the use of reconstructed human epidermis (RHE) models that closely mimic the structure and function of human skin.

At PA Biotechnology, we implement the OECD 431 protocol to provide reliable and accurate evaluations of skin corrosion potential. Our testing services help manufacturers and researchers identify potential hazards associated with their products, ensuring safety for consumer use. The results from the OECD 431 test are essential for the classification and labeling of chemicals, allowing for informed decision-making in product formulation and regulatory submissions. By utilizing this method, we support the development of safe and effective products in the cosmetics, pharmaceuticals, and chemical industries.